Diabetes Research Today is a free monthly online journal that collates and summarizes the latest research about Diabetes, including details on insulin, type i, type ii, diet, treatment, prevention.

The importance of treating multiple cardiometabolic risk factors in patients with Type 2 diabetes.

Mikhailidis DP, Press M

Royal Free Hospital and Royal Free University College Medical School, Department of Clinical Biochemistry, Pond Street, NW3 2QG, London, UK. MIKHAILIDIS@aol.com

Type 2 diabetes is usually associated with a number of metabolic and cardiovascular (or cardiometabolic) risk factors that contribute to a high rate of vascular events in these patients. Adipose tissue is now known to secrete a number of pro-inflammatory adipokines that are thought to mediate the link between obesity, insulin resistance and atherosclerosis. Therefore, not only is abdominal obesity a major cardiometabolic risk factor per se, it has the potential to give rise to other emerging risk factors. Plasma concentrations of inflammatory markers, such as C-reactive protein, may provide additional information to guide management and may even represent therapeutic targets. Reducing the risk of cardiovascular events in patients with Type 2 diabetes will involve targeting traditional risk factors and probably novel cardiometabolic factors.

Published 16 November 2007 in Expert Opin Pharmacother, 8(17): 3009-20.
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